Clinical Efficacy

Proven Clinical Results – Unique Study Design

  • Fully blinded with sham device (Placebo) as control arm
  • Eliminated Placebo Effect – Patients and Clinicians did not know treatment arm
  • Highest Level of Clinical Evidence – Level 1A (Double Blind with Placebo)
eo2 levels of evidence

Statistically Significant Outcomes in 12 Weeks

  • CDO leads to significantly higher rates of closure (2x to 3x)
  • CDO works better in more chronic wounds (lower PWAR*)
  • CDO resulted in significantly faster time to closure (P<0.001)
eo2 closure rate

How Oxygen Works In Wound Healing

Increases Cell Metabolism & Energy
Continuous Pure Oxygen boosts vitality 7

Enhances Bodies Own Anti-Bacterial Capacity
Create Reactive Oxygen Species (i.e. Hydrogen Peroxide) 5,6

Greater Wound Perfusion
Rate of angiogenesis proportional to oxygen concentration 8,9
Better Strength & Appearance
  • Higher tensile strength (reduced recurrence) 10,11
  • Better collagen organization (reduced scarring) 12
Faster Cell Growth & Re-epithelialization
  • Increased collagen deposition (faster repair) 11,13,14
  • Up to 70% faster endothelial gap closure rate 12
Read More about how oxygen works in wound healing

Publications

Effect of CDO on Pain in Treatment of Chronic Wounds

Effect of CDO on Pain in Treatment of Chronic Wounds

Effect of Continuous Diffusion of Oxygen (CDO Therapy) on Pain in Treatment of Chronic Wounds Joanne Bowen RN CWS, Mary…

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CDO Therapy Improves DFU Healing when Compared with a Placebo Control

CDO Therapy Improves DFU Healing when Compared with a Placebo Control

Continuous diffusion of oxygen improves diabetic foot ulcer healing when compared with a placebo control: a randomised, double-blind, multicentre study…

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Clinical Research Summary

Clinical Research Summary

Multicenter DFU Study: Results from a unique Tier 1A Diabetic Foot Ulcer clinical trial involving 100 patients, which show Continuous…

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Case Studies

eo2 case studyOutcome: Wound Closed
Days on Service: 47

eo2 case studyOutcome: Wound Healed
Days on Service: 81

eo2 case studyOutcome: Wound healed
Days on Service: 55

eo2 case studyOutcome: 99% Closure
Days on Service: 93

EO2 Concepts® is an ISO 13485:2003 certified company that maintains European Commission CE mark certification and obtained its Canadian Medical Device License for distribution of innovative wound care products throughout the United States, Canada and the European Union.

iso certification

ce mark

cmdcas

canadian medical license

iso certificationce markcmdcascanadian medical license