Clinical Efficacy

Proven Clinical Results – Unique Study Design

  • Fully blinded with sham device (Placebo) as control arm
  • Eliminated Placebo Effect – Patients and Clinicians did not know treatment arm
  • Highest Level of Clinical Evidence – Level 1A (Double Blind with Placebo)
eo2 levels of evidence

Statistically Significant Outcomes in 12 Weeks

  • CDO leads to significantly higher rates of closure (2x to 4.6x)
  • CDO works better in more chronic, larger and weight-bearing wounds
  • CDO resulted in significantly faster time to closure (P<0.001)
  • Debridement significantly improves CDO outcomes
eo2 closure rate

 Sources: • Centre for Evidence Based Medicine, • Journal of Pharmacology (2013, 4:2,pp 88-169) • Center for Evidence Based Management,  

How Oxygen Works In Wound Healing

Increases Cell Metabolism & Energy
Continuous Pure Oxygen boosts vitality to support increased demand during healing 2-16

Faster Cell Growth & Wound Closure
  • Increased collagen deposition (faster repair) 17-29,59
  • Up to 70% faster endothelial gap closure rate
Rapid Pain Relief
  • Over half of patients experience >75% reduction within 4 days 28-32
  • Significant pain relief in a variety of wounds
Greater Wound Perfusion
Rate of angiogenesis proportional to oxygen concentration 33-40
Enhances Bodies Own Anti-Bacterial Capacity
Create Reactive Oxygen Species (i.e. Hydrogen Peroxide) 19,41-49,51

Better Strength & Appearance
  • Higher tensile strength (reduced recurrence) 50-61
  • Better collagen organization (reduced scarring)
Read more about How Oxygen Works In Wound Healing


CME Credit Webinar: Latest Evidence on CDO Therapy

CME Credit Webinar: Latest Evidence on CDO Therapy

This videos below were recorded from a Live Stream Webinar event by Present E-Learning Systems, introducing some of the latest…

Read more
EO2 – Press Release – OxyGeni Product Launch

EO2 – Press Release – OxyGeni Product Launch

Keeping Wound Care Patients out of the ER: EO2 Announces Next Generation Oxygen Delivery System for Full Wound Closure At-Home…

Read more

Case Studies

eo2 case studyOutcome: Wound Closed
Days on Service: 47

eo2 case studyOutcome: Wound Healed
Days on Service: 81

eo2 case studyOutcome: Wound healed
Days on Service: 55

eo2 case studyOutcome: 99% Closure
Days on Service: 93

EO2 Concepts® is an ISO 13485:2016 certified company that maintains European Commission CE mark certification and obtained its Canadian Medical Device License for distribution of innovative wound care products throughout the United States, Canada and the European Union.


canadian medical license